Clinical Trial: Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee:

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee: Does it Help? A Clinical and Magnetic Resonance Imagi

Brief Summary: This study plans to learn more about ways to treat a joint problem in the knee called Juvenile Osteochondritis Dissecans (OCD). The goal of this study is to see if injecting platelet-rich plasma (PRP) into the knee can help knee cartilage heal faster, and will try to determine whether the injections lead to improvements in pain, performance of activities of daily living, improvements is sports activities and overall function and symptoms reduction. The investigators will compare PRP treatment to conservative therapy.

Detailed Summary:
Sponsor: University of Colorado, Denver

Current Primary Outcome: Greater cartilage healing measured by glycosaminoglycan content on dGEMRIC MRI [ Time Frame: 6 months ]

Measured by dGEMRIC MRI


Original Primary Outcome: Same as current

Current Secondary Outcome: Improvement in pain, performance and overall function [ Time Frame: 6 months ]

Measured by the Pediatric IKDC and KOOS survey results


Original Secondary Outcome: Same as current

Information By: University of Colorado, Denver

Dates:
Date Received: February 24, 2015
Date Started: March 2015
Date Completion: April 2018
Last Updated: March 23, 2017
Last Verified: March 2017