Clinical Trial: A Dye for the Detection of Cancer of the Tongue and Mouth

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: A Phase I/II Study of the Fluorescent PARP1 Binding Imaging Agent PARPi-FL in Patients With Oral Squamous Cell Carcinomas

Brief Summary: The purpose of this study is to test if an investigational dye, called PARPi-FL, can be used to detect this type of cancer. This will be the first time that PARPi-FL is being tried in people. First, the investigators will test the safety of PARPi-FL at different doses to find out what effects, if any, it has on people. The investigators will also see which amount of PARPi-FL is best suited to detect cancers of the mouth and tongue.

Detailed Summary:
Sponsor: Memorial Sloan Kettering Cancer Center

Current Primary Outcome: escalating levels of toxicity (CTCAE v 4.0) [ Time Frame: 1 year ]

toxicity data relevant to study interventions (CTCAE v 4.0)


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Memorial Sloan Kettering Cancer Center

Dates:
Date Received: March 15, 2017
Date Started: March 15, 2017
Date Completion: March 2019
Last Updated: April 24, 2017
Last Verified: April 2017