Clinical Trial: Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title:

Brief Summary:

OBJECTIVES: I. Evaluate the development of oral manifestations of human immunodeficiency virus infection in relationship to the onset of immunologic alterations and systemic symptoms in different risk groups: gay/bisexual men, male intravenous drug users, and female intravenous drug users.

II. Evaluate the immune and inflammatory response to periodontal and other microbial pathogens.

III. Evaluate the bacterial species infecting the oral cavity in patients in these risk groups.

Detailed Summary:

PROTOCOL OUTLINE:

Patients undergo a periodontal assessment every 6 months until medically unable to continue. The oral/dental exam includes saliva and gingival crevicular fluid analysis and, as indicated, oral photographs.

Sponsor: National Institute of Dental and Craniofacial Research (NIDCR)

Current Primary Outcome:

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Office of Rare Diseases (ORD)

Dates:
Date Received: February 24, 2000
Date Started: September 1989
Date Completion:
Last Updated: June 23, 2005
Last Verified: February 1997