Clinical Trial: A Phase II Trial of CyberKnife Radiosurgery to Perioptic Tumors

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: A Phase II Study of Fractionated CyberKnife Stereotactic Radiosurgery to Perioptic Tumors

Brief Summary:

The purpose of this study is to find out what effects (good and bad) CyberKnife stereotactic radiosurgery has on tumors near the critical structures of the eye (optic apparatus).

The investigators hypothesize that hypofractionated stereotactic radiotherapy via the CyberKnife ® can deliver tumor ablating doses of radiation to perioptic lesions safely and effectively while sparing the adjacent optic apparatus and normal brain tissues from receiving damaging doses of radiation.


Detailed Summary: The CyberKnife system is a type of radiation machine that uses a special system to precisely focus large doses of x-rays (radiation) on the tumor. The device is designed to concentrate large doses of radiation onto the tumor so that injury from radiation to the nearby normal tissue will be minimal.
Sponsor: Community Cancer Center, Normal, Illinois

Current Primary Outcome: Local control [ Time Frame: 5 years ]

To determine the local control rate of patients with perioptic lesions treated with stereotactic CyberKnife radiosurgery.


Original Primary Outcome: Same as current

Current Secondary Outcome: Toxicity [ Time Frame: 5 years ]

To determine the acute adverse and delayed effects of this regimen on the optic apparatus


Original Secondary Outcome: Same as current

Information By: Community Cancer Center, Normal, Illinois

Dates:
Date Received: August 22, 2014
Date Started: December 2007
Date Completion: December 2016
Last Updated: August 25, 2014
Last Verified: August 2014