Clinical Trial: Advanced Characterization of Autosomal Dominant Optic Atrophy

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational

Official Title: Cross Sectional Study of Autosomal Dominant Opticus Atrophy

Brief Summary: The purpose of this study is to determine the anatomy of the retina and the optic nerve in patients with autosomal dominant optic atrophy (ADOA). Based on these findings the aim of the study is to determine why patients with the same type of genetic material, i.e. the same mutation, have such large variations of symptoms, spanning from unaffected subjects to blindness. The project requires examination of both healthy and affected family members.

Detailed Summary:
Sponsor: Glostrup University Hospital, Copenhagen

Current Primary Outcome:

  • visual acuity [ Time Frame: 1 day ]
  • vessel caliber [ Time Frame: 1 day ]
  • OCT [ Time Frame: 1 day ]
  • Microperimetry [ Time Frame: 1 day ]
  • Lifestyle questionnaire [ Time Frame: 1 day ]
  • General checkup [ Time Frame: 1 day ]


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Glostrup University Hospital, Copenhagen

Dates:
Date Received: November 30, 2011
Date Started: December 2011
Date Completion: June 2015
Last Updated: January 27, 2012
Last Verified: January 2012