Clinical Trial: Aromatase Inhibitors in the Treatment of Male Infertility

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: The Role of Aromatase Inhibitors in the Treatment of Infertility in Obese Male

Brief Summary: Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production. Aromatase inhibitors such as anastrozole work to decrease the production of estrogen and increase testosterone in the body. By decreasing the level of estrogen, sperm production should improve. In this study, the investigators will try to determine the benefit of anastrozole in obese men and follow pregnancy outcomes.

Detailed Summary:
Sponsor: University of Utah

Current Primary Outcome: Pregnancy Rate [ Time Frame: 4 months ]

Partner pregnancy rate during study participation


Original Primary Outcome: Sperm concentration

Current Secondary Outcome:

Original Secondary Outcome: Other sperm parameters, hormonal measures and pregnancy rates

Information By: University of Utah

Dates:
Date Received: February 22, 2007
Date Started: March 2007
Date Completion:
Last Updated: March 8, 2016
Last Verified: March 2016