Clinical Trial: Clinical and Biochemical Evidence of Neurogenic Inflammation in Women With Urinary Urgency
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Clinical and Biochemical Evidence of Neurogenic Inflammation in Women With Urinary Urgency
Brief Summary: The purpose of this study is to gain a better understanding of what causes urinary urgency in women by asking about different symptoms and measuring biomarker levels in their urine. Understanding the underlying causes of urinary urgency will allow us to develop treatment options to better take care of women with urinary urgency.
Detailed Summary: We propose to test the hypothesis that urinary urgency in women is caused by neurogenic inflammation that is manifested clinically as neuropathic pain and associated with the expression of neuroinflammatory biomarkers in the urine.
Sponsor: University of Pennsylvania
Current Primary Outcome: To determine the association between the severity of neuropathic pain and the severity of urinary symptoms in women with urinary urgency. [ Time Frame: 1 year ]
Original Primary Outcome: Same as current
Current Secondary Outcome: The association between neuropathic pain and the expression of potential neural biomarkers in the urine of women with urinary urgency. [ Time Frame: 1 year ]
Original Secondary Outcome: Same as current
Information By: University of Pennsylvania
Dates:
Date Received: August 27, 2013
Date Started: January 2013
Date Completion:
Last Updated: December 8, 2014
Last Verified: January 2013