Clinical Trial: Brain Perfusion in Pantothenate Kinase-associated Neurodegeneration (PKAN)
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Brain Perfusion in Pantothenate Kinase-Associated Neurodegeneration (PKAN)
Brief Summary: The purpose of this study is to learn whether blood flow in the brain is normal in people with pantothenate kinase-associated neurodegeneration (PKAN). Specifically, preliminary data suggest a region of the brain called the globus pallidus (GP), a key region affected by PKAN, may have reduced blood flow. Standard MRI and perfusion scanning techniques will be used to learn about cerebral blood flow in the globus pallidus and compare it to blood flow in other brain regions as well as to healthy controls.
Detailed Summary:
Sponsor: Susan J. Hayflick
Current Primary Outcome: ASL-derived cerebral blood flow(CBF) [ Time Frame: Single MRI ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Oregon Health and Science University
Dates:
Date Received: April 18, 2013
Date Started: April 2013
Date Completion: October 2017
Last Updated: September 27, 2016
Last Verified: September 2016