Clinical Trial: Natural History and Biological Study of Netherton Syndrome

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Syndrome de Netherton : Aspects Cliniques, Physiopathologiques et Identification de Cibles thérapeutiques

Brief Summary: This study aims at studying the natural history of Netherton syndrome (NS), to identify the consequences of LEKTI deficiency on the immune system and to characterize new molecular mechanisms involved in the disease.

Detailed Summary:
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Current Primary Outcome: Measurement of seric cytokines levels [ Time Frame: 3 months after patient recruitment ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Pattern of skin abnormalities [ Time Frame: 3 months after patient recruitment ]

Original Secondary Outcome: Same as current

Information By: Institut National de la Santé Et de la Recherche Médicale, France

Dates:
Date Received: March 5, 2014
Date Started: April 2014
Date Completion: November 2017
Last Updated: February 3, 2015
Last Verified: February 2015