Clinical Trial: Effects of Cocoa Flavanols on Human Cognitive Function
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title:
Brief Summary: To determine the acute and chronic effects of cocoa derived flavonoids on cognitive function in healthy older adults.
Detailed Summary: This is a randomised controlled double blind cross over study investigating the acute effects of high flavanol (495mg) compared to low flavanol (23mg)cocoa drink on cognitive function in a healthy older adult population (n=60). The primary outcome measure of this study is to determine the effects of the flavanol intervention on cognitive measures of executive function and attention and the secondary measures of blood pressure and to determine whether any observed effects are paralleled by plasma flavanol levels.
Sponsor: University of Reading
Current Primary Outcome: Executive function - attention [ Time Frame: change from baseline to 2 hours ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Blood pressure [ Time Frame: change from baseline to 2 hours ]
- Plasma flavanols [ Time Frame: change from baseline to 2 hours ]
Original Secondary Outcome: Same as current
Information By: University of Reading
Dates:
Date Received: April 27, 2011
Date Started: February 2009
Date Completion:
Last Updated: February 20, 2013
Last Verified: February 2013
