Clinical Trial: Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational [Patient Registry]

Official Title: Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

Brief Summary: The investigators are registering all nephrotic syndrome (NS) patients regardless of the primary causes and developing a NS database in China. Patients will be followed-up and both baseline and follow-up information will be recorded in the registration system. The treatment response, longitudinal changes of renal function, renal survival, patient survival, infection events and acute kidney injury etc, will be analyzed using the NS database.

Detailed Summary: The investigators are registering all NS patients regardless of the primary causes in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education), clinical characteristics (including systolic blood pressure, diastolic blood pressure, primary cause of NS, and lab measurements of serum, urine), pathological characteristics, treatment and treatment response, complications and outcomes. Patients will be followed up, the demographic, clinical characteristics, treatment, lab tests of blood and urine and complications of patients will be collected and recorded at each visit. The investigators also record the outcome at each visit, such as treatment response, longitudinal changes of renal function, hospitalization, occurrence of infection or cardiovascular events etc. The outcomes will be analyzed using the NS database.
Sponsor: Sun Yat-sen University

Current Primary Outcome: The patient survival in NS patients [ Time Frame: 10 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Renal survival in NS patients [ Time Frame: 10 years ]
    Renal survival including end stage renal disease, dialysis, renal transplantation
  • Longitudinal changes of renal function of NS patients [ Time Frame: 10 years ]
  • Treatment response of NS patients [ Time Frame: 10 years ]
  • Infection rate of NS patients [ Time Frame: 10 years ]


Original Secondary Outcome: Same as current

Information By: Sun Yat-sen University

Dates:
Date Received: December 21, 2016
Date Started: April 2016
Date Completion: December 2028
Last Updated: December 22, 2016
Last Verified: December 2016