Clinical Trial: Detection of Micrometastases in Lymph Nodes of Patients With Prostate Cancer

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: Detection of Micrometastases in Lymph Nodes of Patients With Prostate Cancer

Brief Summary: The purpose of this study is to set up a model for detecting micrometastases in Lymph nodes of patients with prostate cancer by quantitative polymerase chain reaction and its impact on progression-free survival.

Detailed Summary:
Sponsor: Technische Universität München

Current Primary Outcome: Biochemical recurrence free survival [ Time Frame: 2 years ]

Influence of molecularbiologic micrometastases in lymph nodes on biochemical recurrence free survival in comparison with patients who have histopathologic macrometastases or no evidence of lymph node metastases


Original Primary Outcome: Same as current

Current Secondary Outcome: Frequency of molecular detected lymph node micrometastases according to their topography [ Time Frame: 2 years ]

Description of the anatomic distribution of molecularbiologic lymph node micrometastases in prostate cancer patients treated with radical prostatectomy and extended lymphadenectomy.

The frequency of molecular detected lymph node micrometastases according to their anatomic distribution at the obturatoric fossa, external iliac, internal iliac and common iliac arteries´ region will be reported.



Original Secondary Outcome: Same as current

Information By: Technische Universität München

Dates:
Date Received: February 27, 2010
Date Started: February 2010
Date Completion: December 2021
Last Updated: July 27, 2015
Last Verified: July 2015