Clinical Trial: Taxotere + Cisplatin in Nasopharyngeal Carcinoma

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Randomized Phase II Study of Concurrent Cisplatin-radiotherapy With or Without Neoadjuvant Chemotherapy Using Taxotere and Cisplatin in Advanced Nasopharyngeal Carcinoma (NPC)

Brief Summary:

Primary objective:

To assess and compare the toxicities of patients with advanced NPC treated with concurrent cisplatin-radiotherapy with or without neoadjuvant Taxotere (docetaxel) and cisplatin.

Secondary objective:

To assess tumor control and survival

Detailed Summary:
Sponsor: Sanofi

Current Primary Outcome: Treatment response is evaluated by correlating findings on clinical examination, endoscopy, biopsy, Computed tomography or Magnetic resonance imaging as appropriate. [ Time Frame: From administration of drug to end of study ]

Original Primary Outcome: Treatment response is evaluated by correlating findings on clinical examination, endoscopy, biopsy, Computed tomography or Magnetic resonance imaging as appropriate.

Current Secondary Outcome: Adverse Events [ Time Frame: From administration of drug to end of study ]

Original Secondary Outcome:

Information By: Sanofi

Dates:
Date Received: February 16, 2007
Date Started: December 2002
Date Completion:
Last Updated: November 16, 2010
Last Verified: November 2010