Clinical Trial: A Comparison of Beclomethasone Aqueous Spray and Aerosol Delivery Systems in Nasal Polyps

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: A Comparison of Beclomethasone Aqueous Spray and Aerosol Delivery Systems in Nasal Polyps

Brief Summary: The purpose of this study is to determine if intranasal Beclomethasone delivered by aerosol or spray is more effective in treatment of nasal polyps.

Detailed Summary:

Aqueous and aerosol delivery of intranasal corticosteroids has never been directly compared previously in patients with nasal polyps and it is unknown whether one is superior.

This objective of this study is to compare the efficacy of intranasal beclomethasone by two different delivery systems, aerosol and aqueous spray in patients with nasal polyps. Primary endpoint is the difference in the overall quality of life as measured by the Rhinitis Quality of Life Questionnaire. The secondary endpoint is the change in Nasal Airflow Resistance as measured by rhinomanometry.

Sponsor: Lawson Health Research Institute

Current Primary Outcome: Difference in overall quality of life as measured by the Rhinitis Quality of Life Questionnaire [ Time Frame: 0, 1, 3, 6 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Difference in Nasal Airflow Resistance as measured an anterior rhinomanometry [ Time Frame: 0, 1, 3, 6 months ]

Original Secondary Outcome: Same as current

Information By: Lawson Health Research Institute

Dates:
Date Received: November 7, 2008
Date Started: March 2008
Date Completion: December 2009
Last Updated: November 7, 2008
Last Verified: November 2008