Clinical Trial: DM1 Heart Registry - DM1 Respiratory Registry
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Cardiac and Respiratory Prognostic Factors in Patients With Myotonic Dystrophy Type 1
Brief Summary:
Myotonic dystrophy type 1 (DM1) is the most frequent neuromuscular disease in adults. DM1 patients have an impaired prognosis (mean age of death <60 years) due to cardiac and respiratory complications.
Our primary objective was to identify cardiac and respiratory prognostic factors in DM1.
Detailed Summary:
- Patients with genetically proven DM1 who were admitted in Pitié Salpêtrière Hospital from 2000 and 2010 will be identified. These patients systematically underwent neurological, cardiac and respiratory investigations.
- Baseline medical and genetic information will be entered in a dedicated database, including cardiac and respiratory investigations.
- The occurence of severe cardiac and respiratory adverse events will also be collected.
- Statistical analysis will be performed to look for correlations between baseline patient characteristics and cardiac or respiratory adverse events during follow up.
Sponsor: Institut de Myologie, France
Current Primary Outcome:
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Institut de Myologie, France
Dates:
Date Received: June 2, 2010
Date Started: May 2010
Date Completion:
Last Updated: February 17, 2012
Last Verified: February 2012
