Clinical Trial: Early Vitrectomy for Macular Tractional Maculopathy

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Early Vitrectomy for Macular Tractional Maculopathy. Multicenter Clinical Trial

Brief Summary:

This study is designed to identify the effect of current vitreous surgery for symptomatic macular tractional maculopathy.

Characteristics of this study is as below

  1. Multicenter, prospective clinical trial. (early surgical intervention vs.surgical intervention when full-thickness macular hole formation or deterioration of visual acuity occurs)
  2. Non-randomized study (decision was made by patients after full explanation)
  3. After 1 year follow up, functional change(visual acuity)and anatomical change would be evaluated

Detailed Summary:

Degenerative myopia is relatively common disorder, especially in Korean, Japanese and Chinese.

Choroidal neovascularization is well-noted cause of VA deterioration, but nowadays, with improvement of diagnostic tools, such as OCT, VA deterioration from myopic tractional maculopathy is being concerned as well.

But till now, the necessity of early vitrectomy on MTM is controversial. By now some clinicians prefer conservative treatment, which means pars plana vitrectomy would be postponed till structural change such as macular hole formation is noticed. And the others prefer early vitrectomy, which means pars plana vitrectomy should be performed when the symptom begins.

In this study, investigators try to verify the validity of early vitrectomy comparing conservative treatment.


Sponsor: Seoul Retina Investigator Group

Current Primary Outcome: Best Corrected Visual acuity [ Time Frame: 48 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Rate of occurrence of full-thickness macular hole [ Time Frame: 48 weeks ]

Original Secondary Outcome: Same as current

Information By: Seoul Retina Investigator Group

Dates:
Date Received: April 30, 2010
Date Started: November 2009
Date Completion: November 2012
Last Updated: March 28, 2011
Last Verified: March 2011