Clinical Trial: Quetiapine Compared With Placebo in the Management of Fibromyalgia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Quetiapine Compared With Placebo in the Management of Fibromyalgia

Brief Summary: Is quetiapine more effective than other medications in the treatment of fibromyalgia.

Detailed Summary: This study is a double blind, placebo controlled, 24-week crossover design. For 12 weeks subjects receive either study medication (200mg Quetiapine) or placebo, after which they will be switched to the other treatment for an additional 12 weeks. Between treatments, subjects are required to undergo a 1-week washout where no drug is given in order to clear the effects of the first treatment. At each visit subjects will complete the following assessment: Fibromyalgia Impact Questionnaire, Pittsburgh Sleep Quality Index, Beck Depression Inventory, State-Trait Anxiety Inventory, and Short Form Health Survey. Temperature, blood pressure, pulse rate, weight and waist circumference will also be recorded. Physical exams and blood tests will be performed at 1, 12, and 25 weeks
Sponsor: East Tennessee State University

Current Primary Outcome: Fibromyalgia Impact Questionnaire [ Time Frame: At 25 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: East Tennessee State University

Dates:
Date Received: October 6, 2011
Date Started: January 2008
Date Completion:
Last Updated: July 8, 2014
Last Verified: July 2014