Clinical Trial: Leucine Supplementation and Skeletal Muscle Disuse

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Leucine and Skeletal Muscle Disuse: Clinical Anti-Atrophic Effectiveness and Related Mechanisms

Brief Summary: Leucine supplementation is widely known for promoting strong influence on skeletal muscle remodeling. This study aims to evaluate the effect of leucine supplementation on disuse-induced skeletal muscle atrophy.

Detailed Summary:
Sponsor: University of Sao Paulo

Current Primary Outcome: Skeletal muscle structure (cross-sectional area) [ Time Frame: 2 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Molecular signalling pathways (hypertrophy, atrophy, and inflammation) [ Time Frame: 2 weeks ]

Original Secondary Outcome: Same as current

Information By: University of Sao Paulo

Dates:
Date Received: August 30, 2010
Date Started: April 2011
Date Completion:
Last Updated: February 22, 2013
Last Verified: February 2013