Clinical Trial: Immobilization and Protein Supplementation (IM-PRO)
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: The Impact of Dietary Protein Supplementation and Age on Muscle Mass Loss During Short Term One-legged Knee Immobilization
Brief Summary: In the present study, the effects of 5 days of lower limb immobilization with or without twice-daily protein supplementation on muscle mass and muscle fiber characteristics will be determined. A young group will be included to compare the changes in muscle mass and muscle fiber characteristics between young and old men.
Detailed Summary:
Sponsor: Maastricht University Medical Center
Current Primary Outcome:
- Change in muscle mass [ Time Frame: three days before immobilization, and directly after immobilization (day of cast removal; day 6) ]
- Change in muscle fiber size [ Time Frame: three days before immobilization, and directly after immobilization (day of cast removal; day 6) ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Change in muscle strength measured by quadriceps 1-Repetition Maximum by Leg Extension [ Time Frame: Three days before immobilization, and directly after immobilization (day of cast removal; day 6) ]
Original Secondary Outcome: Same as current
Information By: Maastricht University Medical Center
Dates:
Date Received: April 26, 2012
Date Started: May 2012
Date Completion:
Last Updated: July 9, 2013
Last Verified: July 2013
