Clinical Trial: Ocular Rigidity and Outflow Facility in Glaucomatous and Normal Eyes
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Measurement of Ocular Rigidity, Outflow Facility and Ocular Blood Flow in Glaucomatous and Normal Eyes
Brief Summary:
Ocular rigidity characterizes the relationship between pressure and volume changes in the human eye and is expressed as a macroscopic coefficient. Outflow facility is a measure of the resistance of the conventional outflow pathway and represents a parameter that is of interest in glaucoma.
Difficulties in the measurement of ocular rigidity in the living human eye have limited our knowledge on this parameter. However, ocular biomechanics have been implicated in the pathogenesis of this disease. The aim of this study is to characterize the pressure volume relation and quantify ocular rigidity and outflow facility in glaucomatous and normal eyes. For this purpose, the investigators have recently developed a manometric method for the measurement of ocular rigidity and outflow facility.
Detailed Summary:
Sponsor: Larissa University Hospital
Current Primary Outcome:
- Ocular rigidity coefficient [ Time Frame: 2 minutes measurement of ocular rigidity ]
- Outflow facility coefficient [ Time Frame: 3-4 minutes measurement of outflow facility ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Ocular pulse amplitude [ Time Frame: 6 minutes ]
- Pulsatile ocular blood flow [ Time Frame: 6 minutes ]
Original Secondary Outcome: Same as current
Information By: Larissa University Hospital
Dates:
Date Received: March 9, 2011
Date Started: March 2011
Date Completion: July 2012
Last Updated: March 16, 2011
Last Verified: March 2011
