Clinical Trial: Rotating Frame Relaxation Imaging in Patients With Multiple Sclerosis

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Rotating Frame Relaxation Imaging in Patients With Multiple Sclerosis

Brief Summary: The aim of this study is to develop novel magnetic resonance imaging (MRI) protocols suitable for patients with multiple sclerosis using advanced MRI such as rotating frame relaxation imaging. In addition, the investigators want to study the correlation between advanced MRI parameters and clinical disease progression.

Detailed Summary:
Sponsor: Turku University Hospital

Current Primary Outcome:

• MR relaxation values 0 [ Time Frame: Baseline ]
  Aim is to measure different quantitative MR relaxation values (e.g. Traff, T1rho) in different brain areas of patients with MS at baseline
• MR relaxation values 1 [ Time Frame: One year ]
  Aim is to measure different quantitative MR relaxation values (e.g. Traff, T1rho) in different brain areas of patients with MS after one year follow-up

Original Primary Outcome: Same as current

Current Secondary Outcome:

• MR relaxation values and clinical markers 0 [ Time Frame: Baseline ]
  Aim is to study the correlation between MR relaxation values and clinical markers of MS at baseline
• MR relaxation values and clinical markers 1 [ Time Frame: One year ]
  Aim is to study the correlation between MR relaxation values and clinical markers of MS after one year follow up

Original Secondary Outcome: Same as current

Information By: Turku University Hospital

Dates:
Date Received: March 10, 2015
Date Started: February 2015
Date Completion: May 2018
Last Updated: October 18, 2016
Last Verified: October 2016