Clinical Trial: The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Key Technology Research of the Comprehensive Treatment of Multiple Organ Dysfunction Syndrome

Brief Summary: The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.

Detailed Summary:
Sponsor: Chinese PLA General Hospital

Current Primary Outcome: the prognostic assessment of aged patients with MODS [ Time Frame: 28 days ]

According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems [(Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ, APACHE Ⅲ), Sample Acute Physiological score(SAPSⅡ), Multiple Organ Dysfunction score(MODS)], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Chinese PLA General Hospital

Dates:
Date Received: February 27, 2013
Date Started: January 2009
Date Completion: December 2013
Last Updated: March 1, 2013
Last Verified: February 2013