Clinical Trial: Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)

Brief Summary: The study aims to identify predictors of disease in patients with hyperparathyroidism (HPTH) who undergo surgery.

Detailed Summary: Researchers aim to identify somatic mutations and inherited genetic variants which may help predict the development of PNET in patients with hyperparathyroidism.
Sponsor: M.D. Anderson Cancer Center

Current Primary Outcome: Identification of Somatic Mutations and Inherited Genetic Variants to Help Predict the Development of Pancreatic Neuroendocrine Tumors (PNET) in Participants with Hyperparathyroidism by Genome Sequencing [ Time Frame: 10 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Identification of Somatic Mutations and Inherited Genetic Variants to Help Predict the Development of Pancreatic Neuroendocrine Tumors (PNET) in Participants with Hyperparathyroidism by Data Review [ Time Frame: 10 years ]

Original Secondary Outcome: Same as current

Information By: M.D. Anderson Cancer Center

Dates:
Date Received: February 13, 2017
Date Started: October 9, 2012
Date Completion: October 2022
Last Updated: February 13, 2017
Last Verified: February 2017