Clinical Trial: Preoperative Prevalence of Ulnar Neuropathy and Changes in Ulnar Nerve Latency During Surgery

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Preoperative Prevalence of Ulnar Neuropathy and Changes in Ulnar Nerve Latency During Surgery

Brief Summary: This study is to investigate the incidence of undiagnosed ulnar neuropathy in patients undergoing surgery. The investigators hope to determine if patients with ulnar neuropathy have changes in nerve conduction latency during surgery.

Detailed Summary: After obtaining an informed consent, the participating subjects will be asked a few questions relating to ulnar nerve dysfunction. Following this the investigators will do a focused physical exam looking for decrement of sensation in the distribution of the ulnar nerve and muscle strength of the hand muscles supplied by the ulnar nerve. After this the subjects will undergo an EMG exam to measure the conduction velocity of the ulnar nerve. Basically the nerve will be stimulated with a small current and the resultant muscle activity of the hand muscle will be picked up using an EKG like patch applied to the skin over the hand. If a subject is diagnosed to have ulnar neuropathy preoperatively the investigators would study the EMG based nerve conduction during surgery at 30-60 minute intervals for the duration of surgery. For purposes of comparison the investigators would measure the ulnar nerve conduction during surgery in age and sex matched controls.
Sponsor: University of Toledo Health Science Campus

Current Primary Outcome: Prevalence of ulnar neuropathy in patients scheduled to undergo anesthesia and surgery as measured by electromyography [ Time Frame: Day 1 ]

Prevalence of undiagnosed or subclinical ulnar neuropathy as determined by electromyography


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Amplitude (mV) [ Time Frame: Day 1 ]
    Compare preoperative, perioperative and postoperative amplitude changes from EMG
  • Latency (ms) [ Time Frame: Day 1 ]
    Compare preoperative, perioperative and postoperative latency changes from EMG
  • Velocity (m/s) [ Time Frame: Day 1 ]
    Compare preoperative, perioperative and postoperative velocity changes from EMG


Original Secondary Outcome: Same as current

Information By: University of Toledo Health Science Campus

Dates:
Date Received: August 20, 2015
Date Started: August 2015
Date Completion: March 2017
Last Updated: January 6, 2017
Last Verified: September 2016