Clinical Trial: Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM.
Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational
Official Title: Large Scale Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From Monoclonal Gammopathy of Undetermined Significance (MGUS) and
Brief Summary: The purpose of this study is to describe DNA copy number variations and gene expression profiles of bone marrow plasma cells of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). The final objective is to search for correlations with the risk of progression in order to establish a predictive model of early malignant transformation.
Detailed Summary:
Sponsor: Rennes University Hospital
Current Primary Outcome: Progression to symptomatic multiple myeloma [ Time Frame: Every 6 or 12 months during 5 years ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Rennes University Hospital
Dates:
Date Received: March 1, 2010
Date Started: November 2010
Date Completion: November 2018
Last Updated: October 27, 2015
Last Verified: October 2015