Clinical Trial: Efficacy of Cantharidin in Molluscum Contagiosum

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Efficacy of Cantharidin in Molluscum Contagiosum: A Randomized, Blinded, Placebo-Controlled Prospective Study

Brief Summary: The University of North Carolina Department of Dermatology is conducting a clinical trial to evaluate a drug called cantharidin in the treatment of molluscum contagiosum. Molluscum is a common dermatologic disorder caused by a poxvirus. Molluscum typically presents with many flesh-colored bumps on the skin. It goes away on its own, though can last several months to several years. Cantharidin is a topical medicine which is applied at the clinic visit. It is well tolerated by the majority of children.

Detailed Summary:
Sponsor: University of North Carolina, Chapel Hill

Current Primary Outcome: Patients Experiencing Complete Clearance of All Molluscum Lesions. [ Time Frame: Baseline compared to 8 weeks (5 visits) ]

Original Primary Outcome: Complete Clearance of All Molluscum Lesions. [ Time Frame: 8 weeks, or 5 visits ]

Current Secondary Outcome: Mean Change in Each Group Measured by Lesion Count. [ Time Frame: Baseline compared to 8 weeks (5 visits) ]

Average change in number of lesions from baseline to 8 weeks


Original Secondary Outcome:

  • Partial clearance of molluscum lesions. [ Time Frame: 8 weeks or 5 visits ]
  • Association of clinical course with presence of atopic dermatitis. [ Time Frame: 8 weeks or 5 visits ]


Information By: University of North Carolina, Chapel Hill

Dates:
Date Received: April 24, 2008
Date Started: January 2008
Date Completion:
Last Updated: June 16, 2011
Last Verified: June 2011