Clinical Trial: Shanghai Mild Cognitive Impairment Cohort Study

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational

Official Title: Shanghai Cohort Study on Mild Cognitive Impairment for Early Detection of Alzheimer's Disease

Brief Summary: This study was planned 1) to identify individuals with Mild Cognitive Impairment (MCI) who convert to Alzheimer's Disease (AD), and 2) to explore factors associated with the conversion.

Detailed Summary:
Sponsor: Translational Research Informatics Center, Kobe, Hyogo, Japan

Current Primary Outcome: Time to Conversion from MCI to "Probable AD Dementia" [ Time Frame: 3 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Time to Conversion from MCI to "Possible AD Dementia" or "Probable AD Dementia" [ Time Frame: 3 years ]
  • Time to Conversion from MCI to "All-cause Dementia" [ Time Frame: 3 years ]
  • Overall survival [ Time Frame: 3 years ]
  • Changes in Neuropsychological examinations [ Time Frame: baseline, annual and 3 years ]
  • Changes in MRI [ Time Frame: baseline, annual and 3 years ]


Original Secondary Outcome:

  • Time to Conversion from MCI to "Possible AD Dementia" or "Probable AD Dementia" [ Time Frame: 3 years ]
  • Time to Conversion from MCI to "All-cause Dementia" [ Time Frame: 3 years ]
  • Overall survival [ Time Frame: 3 years ]
  • Changes in Neuropsychological examinations [ Time Frame: 3 years ]
  • Changes in MRI [ Time Frame: 3 years ]


Information By: Translational Research Informatics Center, Kobe, Hyogo, Japan

Dates:
Date Received: February 15, 2012
Date Started: February 2012
Date Completion:
Last Updated: September 17, 2015
Last Verified: September 2015