Clinical Trial: Induction of Migraine Aura With Sildenafil

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: The Effect of the Selective PDE5 Inhibitor, Sildenafil, on Aura and Migraine Headache Induction.

Brief Summary: In a double blind placebo-controlled cross-over study the effect of Sildenafil on aura and migraine headache induction is tested in patient with migraine with aura.

Detailed Summary:
Sponsor: Herlev Hospital

Current Primary Outcome: Aura and migraine like headache [ Time Frame: 14 hours ]

Induction of aura reported by an aura diary for 14 hours post medication


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Markers of endothelial function in blood [ Time Frame: 2 hours ]
  • Migraine without aura [ Time Frame: 14 hours ]
    Induction of headache resembling usual migraine attacks


Original Secondary Outcome: Same as current

Information By: Herlev Hospital

Dates:
Date Received: April 9, 2016
Date Started: June 2015
Date Completion:
Last Updated: June 6, 2016
Last Verified: June 2016