Clinical Trial: Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular Angina
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional
Official Title: Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular Angina
Brief Summary: This study is undertaken to determine if ticagrelor augments adenosine-induced coronary flow reserve (CFR), ameliorates clinical symptomatology and exercise tolerance in patients with MVA
Detailed Summary: Considering the reduced CFR and increased platelet aggregability in patients with MVA, together with the augmented effect on adenosine-mediated coronary blood flow and potent antiplatelet effect of ticagrelor, we speculate that ticagrelor can promisingly ameliorate the coronary microvascular function in patients with MVA.
Sponsor: Second Xiangya Hospital of Central South University
Current Primary Outcome: adenosine-induced coronary flow reserve (CFR) [ Time Frame: 2 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Second Xiangya Hospital of Central South University
Dates:
Date Received: November 2, 2014
Date Started: November 2014
Date Completion: November 2017
Last Updated: November 5, 2014
Last Verified: November 2014