Clinical Trial: Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular Angina

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular Angina

Brief Summary: This study is undertaken to determine if ticagrelor augments adenosine-induced coronary flow reserve (CFR), ameliorates clinical symptomatology and exercise tolerance in patients with MVA

Detailed Summary: Considering the reduced CFR and increased platelet aggregability in patients with MVA, together with the augmented effect on adenosine-mediated coronary blood flow and potent antiplatelet effect of ticagrelor, we speculate that ticagrelor can promisingly ameliorate the coronary microvascular function in patients with MVA.
Sponsor: Second Xiangya Hospital of Central South University

Current Primary Outcome: adenosine-induced coronary flow reserve (CFR) [ Time Frame: 2 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Second Xiangya Hospital of Central South University

Dates:
Date Received: November 2, 2014
Date Started: November 2014
Date Completion: November 2017
Last Updated: November 5, 2014
Last Verified: November 2014