Clinical Trial: Long-term Postoperative Outcomes After Bilateral Congenital Cataract Surgery in Eyes With Microphthalmos

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: A Long-term Postoperative Outcome After Bilateral Congenital Cataract Surgery in Eyes With Microphthalmos

Brief Summary:

Cataract surgery in infantile eyes, which are microphthalmic, can be even more demanding.

In addition, the frequent presence of other ocular and systemic anomalies such as nystagmus, glaucoma, amblyopia, and higher rate of postoperative complications may limit the success of cataract surgery.

In our previous study, the investigators examined the intraoperative performance and postoperative outcomes of bilateral cataract surgery in microphthalmic eyes of patients before their first birthday. At 1 year, the postoperative results showed that good visual outcomes could be obtained in microphthalmic eyes.

Since only a few studies have reported outcomes, and that too only short term of cataract surgery on microphthalmic eyes, in this prospective observational study we evaluated the long-term impact of bilateral cataract surgery on eyes with microphthalmos. The investigators examined the outcomes, complication rates, influence of age at surgery on pattern of axial growth and central corneal thickness and visual and orthoptic assessment in these eyes.


Detailed Summary:
Sponsor: Iladevi Cataract and IOL Research Center

Current Primary Outcome: Glaucoma following cataract surgery [ Time Frame: 45 months postoperative ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Posterior synechiae [ Time Frame: 45 months postoperatively ]
  • visual axis obscuration [ Time Frame: 45 months ]
  • axial length rate of growth [ Time Frame: 45 months postoperatively ]
  • central corneal thickness [ Time Frame: 45 months postoperatively ]
  • visual acuity [ Time Frame: 45 months postoperatively ]


Original Secondary Outcome: Same as current

Information By: Iladevi Cataract and IOL Research Center

Dates:
Date Received: March 21, 2013
Date Started: January 2003
Date Completion:
Last Updated: March 25, 2013
Last Verified: March 2013