Clinical Trial: Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis Without Acquired Immune Deficiency Syndrome

Brief Summary: The main purpose of this study is to observe the clinical effect of intrathecal administration of liposomal amphotericin B in Cryptococcal Meningitis without Acquired Immune Deficiency Syndrome (AIDS).

Detailed Summary:
Sponsor: Hui Bu

Current Primary Outcome: laboratory examination of cerebrospinal fluid [ Time Frame: 2 to 4 weeks ]

It includes routine test，biochemistry indicators and cytology ，namely white blood cell count per litre， protein（in g/l），glucose（in mmol/l）and chloride（in mmol/l）in cerebrospinal fluid ，an assessment will be assessed every week


Original Primary Outcome: Same as current

Current Secondary Outcome: changes of clinical symptoms [ Time Frame: 2 to 4 weeks ]

headache duration, duration of fever,presence of cranial nerve damage


Original Secondary Outcome: Same as current

Information By: Hebei Medical University

Dates:
Date Received: January 26, 2016
Date Started: January 2016
Date Completion:
Last Updated: February 16, 2016
Last Verified: February 2016