Clinical Trial: Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title:

Brief Summary: The main purpose of this study is to compare the effect of 10 mg and 15 mg methotrexate in the treatment of meningeal carcinomatosis.

Detailed Summary:
Sponsor: Hui Bu

Current Primary Outcome: overall survival [ Time Frame: one year ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

• The incidence of adverse reactions [ Time Frame: one year ]
  In accordance with the standard of CTCAE, an assessment will be assessed every month
• KPS score [ Time Frame: one year ]
  In accordance with the standard of KPS(Karnofsky Performance Status,KPS) score, an assessment will be assessed every month

Original Secondary Outcome:

• The incidence of adverse reactions [ Time Frame: one year ]
  In accordance with the standard of CTCAE, an assessment will be assessed every month
• KPS score [ Time Frame: one year ]
  In accordance with the standard of KPS score, an assessment will be assessed every month

Information By: Hebei Medical University

Dates:
Date Received: October 26, 2015
Date Started: October 2015
Date Completion:
Last Updated: October 27, 2016
Last Verified: October 2016