Clinical Trial: Study on Single-nucleotide-polymorphism in Idiopathic Membranous Nephropathy

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Mechanism Research of Traditional Chinese Medicine (the Comprehensive Treatment Regimen) in Treating Idiopathic Membranous Nephropathy by Genomewide Association Studies

Brief Summary: The purpose of this study is to analysis the different genotype in the idiopathic membranous nephropathy patients which with different therapeutic outcomes after treated by the Comprehensive Treatment Regimen or immunosuppressive agents, and so as to looking for ideal markers to assess appropriate treatment approach and the long-term efficacy.

Detailed Summary: The primary objective of this study is to looking for the gene level predictors in the patients who suffered from idiopathic membranous nephropathy. And according to the predictors, the clinicians could make a decision which method should be taken on IMN patients, Traditional Chinese Medicine or western medicine, and could get better results.
Sponsor: Shanghai University of Traditional Chinese Medicine

Current Primary Outcome: Genome-wide single-nucleotide-polymorphism of IMN patients treated by the Comprehensive Treatment Regimen or conventional approach [ Time Frame: one year ]

Screening for single-nucleotide-polymorphism as the prognostic factor for the TCM intervention of IMN patients.


Original Primary Outcome: Gene expression profile of IMN patients treated by "shenqimoshen decoction" or conventional approach [ Time Frame: one year ]

Screening for specifically expressed genes as the prognostic factor for the TCM intervention of IMN patients.


Current Secondary Outcome:

Original Secondary Outcome:

Information By: Shanghai University of Traditional Chinese Medicine

Dates:
Date Received: January 8, 2013
Date Started: December 2010
Date Completion: August 2013
Last Updated: April 22, 2013
Last Verified: April 2013