Clinical Trial: Efficacy and Safety of Fractional Carbon Dioxide Laser for Treatment of Facial Freckles.

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Efficacy and Safety of Fractional Carbon Dioxide Laser for Treatment of Facial Freckles

Brief Summary:

Freckles are clusters of melanin in the superficial epidermis. They affect mostly face and sun exposed areas, and appear as flat brown or red macules that fade in winter, usually in a fair complexion patient, but may be present in other skin types.

The gold standard in the industry for non-surgical facial rejuvenation, removal of wrinkles, pigmentation, and general sun damage has been the carbon dioxide (CO2) laser since the mid 1990s. The traditional CO2 laser was very effective, however it fell out of favor because it required general anesthesia. It also had a prolonged recovery time. Over the last several years, advances in technology known as fractional resurfacing has made the CO2 laser popular again: Fractional CO2 laser treatment is one of the newest laser rejuvenation technology. It proved successful in treatment of melasma, one of the pigmented dermatoses. To the best of our knowledge, based on a thorough search of literature, no clinical studies assessing fractional CO2 laser in treatment of freckles could be retrieved.


Detailed Summary:
Sponsor: Cairo University

Current Primary Outcome: treatment success [ Time Frame: One month ]

reduction of freckles number and color density more than 50% in comparison to pre-treatment digital photos


Original Primary Outcome: Same as current

Current Secondary Outcome: Treatment safety [ Time Frame: three months ]

Absence of irreversible changes in color and texture of the facial skin, that can cause patient dissatisfaction


Original Secondary Outcome: Same as current

Information By: Cairo University

Dates:
Date Received: March 2, 2012
Date Started: March 2012
Date Completion:
Last Updated: April 4, 2014
Last Verified: April 2014