Clinical Trial: Comparative Microarray Analysis in Primary Cutaneous Malignant Melanoma

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Comparative Microarray Analysis of microRNA Expression Profiles in Primary Cutaneous Malignant Melanoma, Cutaneous Malignant Melanoma Metastas

Brief Summary: Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). This study will be an exploratory analysis by miRNA expression profiling using microarrays.

Detailed Summary: Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). With regards to a rapidly growing number of newly discovered miRNA sequences, the availability of up-to-date miRNA expression profiles for primary cutaneous malignant melanoma (PCMM), cutaneous malignant melanoma metastases (CMMM) and benign melanocytic naevi (BMN) is limited. Patients with PCMM, CMMM and BMN are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).
Sponsor: Ruhr University of Bochum

Current Primary Outcome:

Original Primary Outcome:

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Original Secondary Outcome:

Information By: Ruhr University of Bochum

Dates:
Date Received: November 26, 2011
Date Started: December 2011
Date Completion:
Last Updated: November 5, 2012
Last Verified: November 2012