Clinical Trial: Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Study on the Effect of Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome Parallel Synchronized Intermittent Mandatory Ventilation; Synchronous Maudato
Brief Summary: Helium—oxygen mixture(heliox) was suggested to be beneficial in meconium aspiration syndrome in previous studies，but the evidence was limited．The aim of the study was to assess the effectiveness of synchronize intermittent mandatory ventilation (SIMV) with heliox (70% helium and 30% oxygen) on length of ventilation(LoV) and cardiopulmonary protection in meconium aspiration syndrome.
Detailed Summary:
Sponsor: Ma Juan
Current Primary Outcome:
- blood gas analysis [ Time Frame: 2 hour ]Time detection after treatment
- blood gas analysis [ Time Frame: 6 hour ]
- blood gas analysis [ Time Frame: 12 hour ]
- blood gas analysis [ Time Frame: 24 hour ]
- blood gas analysis [ Time Frame: 48 hour ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Inflammatory response index (IL-6, MDA, TNF-, MPO, iNOS) [ Time Frame: 0 hour ]
- Inflammatory response index (IL-6, MDA, TNF-, MPO, iNOS) [ Time Frame: 6 hour ]
Original Secondary Outcome: Same as current
Information By: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Dates:
Date Received: November 12, 2015
Date Started: February 2015
Date Completion: December 2016
Last Updated: December 2, 2015
Last Verified: December 2015
