Clinical Trial: Early Waning of Maternal Measles and Meningitis C Antibodies
Study Status: Not yet recruiting
Recruit Status: Unknown status
Study Type: Observational
Official Title: Observation Study on Early Waning of Maternal Measles and Meningitis C Antibodies
Brief Summary:
Maternal antibodies (measles and meningitis C) may wane in the first six months after birth.
- Geometric mean titers(GMTs) of measles and meningitis C.
- Follow-up on 0 month, 3rd month,5th month and 7th month after birth.
Detailed Summary:
Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged < 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies.
Maternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.
Sponsor: Guangzhou Center for Disease Control and Prevention
Current Primary Outcome: Geometric Mean Titer [ Time Frame: Up to six months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Guangzhou Center for Disease Control and Prevention
Dates:
Date Received: August 13, 2014
Date Started: May 2014
Date Completion: December 2014
Last Updated: September 16, 2014
Last Verified: August 2014
