Clinical Trial: High Quality Evidence of Chinese Lupus Nephritis (HELP)

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: High Quality Evidence of Chinese Lupus Nephritis (HELP)

Brief Summary: The investigators are registering LN patients at recruited hospitals and developing a LN database in China. Patients will be follow-up every year, and both baseline and follow-up information will be entered into the registration system.

Detailed Summary: The investigators are registering Lupus nephritis (LN) and developing a LN database in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education etc.), clinical characteristics (including systolic blood pressure, diastolic blood pressure, and lab measurements of whole blood, serum, urine etc.), complications, drug information at the baseline will be collected. Patients will be follow-up every year, the demographic and clinical characteristics, complications; drug information of patients will be collected at each visit. We will also record the outcome at each visit, such as mortality (including all-cause mortality and cardiovascular disease mortality), end-stage renal disease (ESRD) or serum creatinine doubling. The patient survival and renal survival will be compared using the LN database.
Sponsor: Sun Yat-sen University

Current Primary Outcome:

• All-cause mortality and cardiovascular mortality of LN patients [ Time Frame: 10years ]
• A composite renal outcome of LN patients [ Time Frame: 10years ]
  The composite renal outcome defined as doubling of serum creatinine and ESRD (defined as initiation of dialysis or kidney transplantation).

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Sun Yat-sen University

Dates:
Date Received: December 21, 2016
Date Started: November 2013
Date Completion: December 2026
Last Updated: December 22, 2016
Last Verified: December 2016