Clinical Trial: The Safety and Efficacy of Etanercept (Enbrel®) for the Treatment of Discoid Lupus Erythematosus

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: A Phase 2 Open Label Study to Assess the Efficacy and Safety of Etanercept (Enbrel®)for the Treatment of Discoid Lupus Erythematosus

Brief Summary: A 20 week study to assess the safety and efficacy of etanercept(Enbrel®)for the treatment of Discoid Lupus Erythematosus

Detailed Summary:
Sponsor: Florida Academic Dermatology Centers

Current Primary Outcome: Proportion of patients responding to study treatment using the Cutaneous Lupus Erythematous Disease Area Severity Index(CLASI)defined as a decrease of 50% form baseline. [ Time Frame: 20 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Change from baseline to week 20 in Dermatology Life Quality Index and Pysician's Global Assessment of disease measurements [ Time Frame: 20 weeks ]

Original Secondary Outcome: Same as current

Information By: Florida Academic Dermatology Centers

Dates:
Date Received: November 21, 2008
Date Started: October 2008
Date Completion: April 2011
Last Updated: May 25, 2010
Last Verified: November 2008