Clinical Trial: Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Effects of Neuromuscular Electrical Stimulation on Functional Exercise Capacity and Quality of Life in Patients With Interstitial Lung Disease

Brief Summary: Decreased exercise capacity and quality of life, increased dyspnea and fatigue perception and hypoxemia during exercise is seen in patients with interstitial lung disease. Impaired ventilatory response, increased lung compliance, ventilation-perfusion mismatching and inadequate peripheral circulation causes decreased exercise capacity. Another important factor that induce decreased exercise capacity is peripheral muscle weakness. In literature, there is no study investigated effects of neuromuscular electrical stimulation on functional exercise capacity, respiratory and peripheral muscle strength, pulmonary functions, physical activity level, dyspnea and fatigue perception in patients with interstitial lung disease.

Detailed Summary: In literature, there was increased quantity of study investigated effects of neuromuscular electrical stimulation in chronic lung disease patients. It was used as a pulmonary rehabilitation component especially in patients with decreased exercise capacity and peripheral muscle strength, intensely increased dyspnea inhibits exercise. It was demonstrated that neuromuscular electrical stimulation improved functional exercise capacity, peripheral muscle strength and quality of life.
Sponsor: Gazi University

Current Primary Outcome: Functional exercise capacity [ Time Frame: 6 weeks ]

Six minute walk test


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Pulmonary functions [ Time Frame: 6 weeks ]
    Spirometry
  • Inspiratory and expiratory muscle strength (MIP,MEP) [ Time Frame: 6 weeks ]
    Mouth pressure device
  • Dyspnea [ Time Frame: 6 weeks ]
    Modified Borg and Modified Medical Research Council (MMRC) Dyspnea scales
  • Peripheral muscle strength [ Time Frame: 6 weeks ]
    Hand held dynamometer
  • Maximal exercise capacity [ Time Frame: 6 weeks ]
    Incremental shuttle walk test
  • Fatigue [ Time Frame: 6 weeks ]
    Fatigue Severity Scale
  • Physical activity [ Time Frame: 6 weeks ]
    Metabolic holter
  • Quality of life [ Time Frame: 6 weeks ]
    Leicester Cough Questionnaire
  • Depression [ Time Frame: 6 weeks ]
    Montgomery Asberg Depression Rating Scale (MADRS) (Turkish versions of all scales)
  • Quality of life [ Time Frame: 6 weeks ]
    Short Form (SF-36) Health Survey
  • Quality of life [ Time Frame: 6 weeks ]
    Saint George Quality of Life Questionnaire


Original Secondary Outcome: Same as current

Information By: Gazi University

Dates:
Date Received: July 8, 2015
Date Started: July 2015
Date Completion: December 2017
Last Updated: July 10, 2015
Last Verified: July 2015