Clinical Trial: BREAST CANCER AND EXERCISE

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: BREAST CANCER AND EXERCISE BREX: A Multicenter Phase III Open Randomised Trial of the Efficacy of Exercise in the Prevention of Long-Term Adverse Effects of Adjuvant Treat

Brief Summary: A Finnish Breast Cancer Group Study (BREX 01-2004). A multicenter phase III open randomised trial of the efficacy of exercise in the prevention of long-term adverse effects of adjuvant treatments and breast cancer recurrences in women with primary breast cancer. The aim of the study is to investigate whether regular exercise training could reduce the long-term side effects of adjuvant treatments of primary breast cancer and improve quality of life and well being.

Detailed Summary: A multicenter phase III open randomised trial of the efficacy of exercise in the prevention of long-term adverse effects of adjuvant treatments and breast cancer recurrences in women with primary breast cancer. The aim of the study is to investigate whether regular exercise training could reduce the long-term side effects of adjuvant treatments of primary breast cancer and improve quality of life and well being. Large controlled prospective studies are needed to confirm the preliminary findings of exercises benefits in cancer patients, and to investigate the type, the frequency, intensity and tolerability of exercise training in cancer patients, before any clinical recommendations can be given. Prevention of osteoporosis, improvement of weight control, and muscular and cardiovascular fitness is been waited. The second aim of the study is to investigate, whether regular exercise training reduces the risk of breast cancer recurrence, prevents other diseases and reduce all-cause mortality and is cost effective in women with primary breast cancer.
Sponsor: Finnish Breast Cancer Group

Current Primary Outcome: The aim of the study is to investigate whether regular exercise after adjuvant treatments of breast cancer could prevent osteoporosis and improve quality of life. [ Time Frame: 1-10 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Fitness and weight control, number of falls and fractures, breast cancer recurrence. [ Time Frame: 1-10 years ]

Original Secondary Outcome: Same as current

Information By: Finnish Breast Cancer Group

Dates:
Date Received: March 14, 2008
Date Started: September 2005
Date Completion:
Last Updated: March 19, 2008
Last Verified: March 2008