Clinical Trial: Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients With KCNQ1 or KCNH2 Mutation Without Long QT Interval in Rest ECG
Brief Summary: The aim of the study is to evaluate the best stress exam to unmask long QT in patient with KCNQ1 or KCNH2 mutation without long QT interval in rest electrocardiogram.
Detailed Summary:
65 patients with KCNQ1 or KCNH2 mutation presenting QTc interval <470msec and 65 patients without KCNQ1 or KCNH2 mutation presenting QTc interval <470msec will be included.
All patients will have the 2 tests: exercise test and epinephrine test, in one half day.
At the end of the inclusions, two experts will examine examens results without knowing in which arm (mutated or not) the patient belongs.
Sponsor: Nantes University Hospital
Current Primary Outcome: to evaluate the best stress exam (exercise test OR epinephrine test)to unmask long QT syndrome. [ Time Frame: day 1 ]
Original Primary Outcome: Same as current
Current Secondary Outcome: to evaluate each test characteristics [ Time Frame: Day 1 ]
Original Secondary Outcome: Same as current
Information By: Nantes University Hospital
Dates:
Date Received: December 5, 2012
Date Started: May 2012
Date Completion: May 2018
Last Updated: October 4, 2016
Last Verified: October 2016