Clinical Trial: Study of T Cell Phenotype Activation Pathway in Human Alcoholic Liver Disease
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Study of T Cell Phenotype Activation Pathway in Human Alcoholic Liver Disease
Brief Summary: Alcoholic liver disease is characterized by circulating T cell activation and liver T cell infiltration but their phenotype is poorly studied. The aim of the study is to test the hypothesis that the (CD4+ T cell secreting Interleukin-17) Th17 pathway is involved in alcoholic liver disease.
Detailed Summary: Consecutive patients undergoing transjugular liver biopsies for alcoholic liver disease or hepatitis C virus infection will be included in the study to measure plasma cytokines levels, peripheral blood mononuclear cells cytokine release and liver T cell infiltrates.
Sponsor: Erasme University Hospital
Current Primary Outcome:
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Erasme University Hospital
Dates:
Date Received: January 28, 2008
Date Started: January 2005
Date Completion:
Last Updated: January 28, 2008
Last Verified: January 2008