Clinical Trial: Pangenomic Study During Alcoholic Cirrhosis
Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational
Official Title: Genetical Predisposition in Hepatocellular Carcinoma : Pangenomic Link Study During Alcoholic Cirrhosis
Brief Summary:
Hepatocellular carcinoma (HCC) is a frequent complication of cirrhosis. Occurrence of HCC could be linked with multiple functional region of genome.
The determining of a genomic mapping of " single nucleotide polymorphisms " (SNPs) permit to perform some genetic link studies with pathologies without clear hereditary disposition.
In this study, the investigators will identify predictives genetic polymorphism of HCC.
Detailed Summary:
Sponsor: Nantes University Hospital
Current Primary Outcome: Existence of HCC and Pangenomic analysis of DNA polymorphism
Original Primary Outcome: Existence of HCC and determination of which genetic polymorphism are predisposing to HCC or preventing for HCC
Current Secondary Outcome: cirrhosis severity (compensated or not)
Original Secondary Outcome: cirrhosis severity (compensated or not)
Information By: Nantes University Hospital
Dates:
Date Received: February 8, 2010
Date Started: May 2008
Date Completion: May 2012
Last Updated: August 12, 2011
Last Verified: April 2010