Clinical Trial: Lethargic Depression Study

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: An 8 Week, Multicenter, Randomized, Double-blind, Placebo Controlled Comparison of the Efficacy of Extended Release Bupropion Hydrochloride and Placebo in the Treatment of Adult Outpatients With Major

Brief Summary: This is a study of Major Depressive Disorder (MDD) in patients with decreased energy, pleasure and interests.

Detailed Summary: A Multicenter, Double-Blind, Placebo-controlled comparison of the efficacy and safety of flexible dose extended-release bupropion (HCl) 300-450 mg/day and placebo administered for eight weeks for the treatment of adult outpatients with major depressive disorder including symptoms of decreased energy, pleasure, and interest
Sponsor: GlaxoSmithKline

Current Primary Outcome: Change from randomization on the Inventory of Depressive Symptomatology, self report and clinician rated.

Original Primary Outcome:

Current Secondary Outcome: Percent of responders. Percent of remitters. Quality of Life Enjoyment and Satisfaction Questionnaire.

Original Secondary Outcome:

Information By: GlaxoSmithKline

Dates:
Date Received: July 8, 2003
Date Started: June 2003
Date Completion:
Last Updated: January 18, 2017
Last Verified: January 2017