Clinical Trial: New Proteins in Body Fluids as Potential Biomarker for Alzheimer's Disease: a Pilot Study
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational
Official Title: New Proteins in Body Fluids as Potential Biomarker for Alzheimer's Disease: a Pilot Study
Brief Summary: Alzheimer's disease (AD) is the most common neurodegenerative disorder afflicting the elderly. Currently, some biochemical tests performed on Cerebrospinal Fluid (CSF) samples have demonstrated to discriminate to some extend between AD and non-AD individuals based on the levels of tau, phospho-tau or Aβ42. We aim to investigate newly identified proteins whose levels increase during the Braak Stages of AD that are accessible in other body fluids such as blood, urine or saliva. The detection of these proteins would allow performing simple tests in case its levels were confirmed to be associated with the AD pathology.
Detailed Summary: We do not desire to provide a more extensive description
Sponsor: Universitaire Ziekenhuizen Leuven
Current Primary Outcome: Differences in blood, saliva and urine protein levels in patients with Alzheimer's Disease versus healthy controls. [ Time Frame: Up to 1 year ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Universitaire Ziekenhuizen Leuven
Dates:
Date Received: December 26, 2012
Date Started: December 2012
Date Completion: June 2014
Last Updated: January 13, 2014
Last Verified: January 2013