Clinical Trial: Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Some Aromatic Medical Plants.

Brief Summary:

This randomized, double blind, parallel group study, compared the efficacy of spray containing aromatic essential oils of some herbal plants, against placebo in the treatment of patients with acute viral Laryngitis or Tracheitis.

Study objectives: Primary to demonstrate a hoarseness or cough relief within 20 minutes after first administration of treatment with the spray.

Secondary to demonstrate a reduction of a defined symptoms sum score based on symptoms and signs comparing baseline therapy from the beginning to the end of 3 days treatment

Detailed Summary:

This study compared the efficacy of spray containing aromatic essential oils of Eucalyptus citriodora, Eucalyptus globulus, Mentha piperita, Origanum syriacum, and Rosmarinus Officinalis, against placebo in the treatment of patients with acute viral Laryngitis or Tracheitis.

In- vitro and clinical studies suggest therapeutic potential of aromatic herbs and trees oils in the treatment of Laryngitis or Tracheitis. The pharmacological and clinical activity of Eucalyptus citriodora, Eucalyptus globulus, Mentha piperita, Origanum syriacum, and Rosmarinus Officinalis, include anti-inflammatory, anti-bacterial and anti-viral activities. Some of these herbs and trees oils have direct activity on the respiratory tract, the coughing reflex and the airflow in the nasal tract.

Sponsor: HaEmek Medical Center, Israel

Current Primary Outcome: To demonstrate a cough or hoarseness relief within the first 20 minutes after first administration of treatment with the spray. [ Time Frame: 20 minutes ]

Original Primary Outcome: Same as current

Current Secondary Outcome: To demonstrate a reduction of a defined symptoms sum score based on symptoms and signs comparing baseline therapy from the beginning to the end of 3 days treatment. [ Time Frame: 3 days ]

Original Secondary Outcome: Same as current

Information By: HaEmek Medical Center, Israel

Dates:
Date Received: January 8, 2008
Date Started: January 2008
Date Completion:
Last Updated: June 13, 2008
Last Verified: June 2008