Clinical Trial: Laryngeal Mask Airway (LMA) Insertion With Sevoflurane and Remifentanil

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Target-controlled Infusion of Remifentanil for Laryngeal Mask Airway Insertion During Sevoflurane Induction in Adults

Brief Summary: The purpose of this study was to determine the most suitable effect-site concentration of remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.

Detailed Summary: For practical purposes, opioids with the ability to suppress upper airway reflexes have been used to facilitate insertion of the LMA during anaesthesia induction. To date, however, there have been no published reports addressing the use of remifentanil to facilitate LMA insertion during sevoflurane inhalation induction in adults. Therefore, the purpose of this study was to determine the most suitable effect-site concentration of remifentanil target-controlled infusion (TCI) for the LMA insertion during inhaled induction with 8% sevoflurane in adults.
Sponsor: Gachon University Gil Medical Center

Current Primary Outcome: LMA Insertion Condition [ Time Frame: at that time on LMA insertion only ]

The pre-determined effect-site concentration of remifentanil or normal saline was administered according to the patient's group.LMAs were size #3 for women and #4 for men.The conditions of the LMA insertion were graded on a three point scale using six variables (mouth opening, ease of LMA insertion, swallowing, coughing and gagging, head and body movements, laryngospasm). Each of these variables was rated as excellent, intermediate or poor.


Original Primary Outcome: Same as current

Current Secondary Outcome: Frequency of Apnea [ Time Frame: baseline, 30sec after drug injection ]

If prolonged apnoea (> 30 s) developed, manual ventilation was assisted. And record the frequency of apnea on each group


Original Secondary Outcome: Same as current

Information By: Gachon University Gil Medical Center

Dates:
Date Received: October 19, 2011
Date Started: April 2011
Date Completion:
Last Updated: April 17, 2014
Last Verified: April 2014