Clinical Trial: MRI Imaging of the Human Larynx

Study Status: Terminated
Recruit Status: Terminated
Study Type: Observational

Official Title: High Resolution MRI in the Evaluation of Laryngeal Neoplasia

Brief Summary: To determine if high resolution MRI can detect early invasion of cartilage by laryngeal carcinoma, and to determine if high resolution MRI may be superior to conventional MRI imaging or CT imaging to detect cartilage invasion.

Detailed Summary:
Sponsor: Stanford University

Current Primary Outcome:

  • Tumor stage as determined by histopathology in excised larynges. [ Time Frame: 4 to 6 weeks ]
  • Estimate the precision of HRMRI in terms of cartilage invasion. [ Time Frame: 4 to 6 weeks ]
  • Tumor stage as determined by HRMRI. [ Time Frame: 24 to 48 hours ]
  • Estimate the precision of HRMRI in discriminating between edema and tumor in patients with prior radiotherapy or chemotherapy. [ Time Frame: 4 to 6 weeks ]


Original Primary Outcome:

  • Tumor stage as determined by HRMRI.
  • Tumor stage as determined by histopathology in excised larynges.
  • Estimate the precision of HRMRI in terms of cartilage invasion.
  • Estimate the precision of HRMRI in discriminating between edema and tumor in patients with prior radiotherapy or chemotherapy.


Current Secondary Outcome:

Original Secondary Outcome:

Information By: Stanford University

Dates:
Date Received: August 21, 2009
Date Started: July 2009
Date Completion:
Last Updated: December 12, 2013
Last Verified: December 2013