Clinical Trial: Prospective Evaluation of Adult Pulmonary Langerhans Cell Histiocytosis
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Epidemiology of Adult Adult Pulmonary Langerhans Cell Histiocytosis - A Multicenter Cohort Study
Brief Summary:
Study objectives:
- To estimate the incidence of pulmonary deterioration in adult pulmonary Langerhans cell histiocytosis
- To assess the impact of tobacco discontinuation
- Study Design Multicentric prospective cohort study
- Main endpoint: Pulmonary deterioration
- Sample size : 40 patients
Detailed Summary: Study objectives To estimate the incidence of pulmonary deterioration in adult pulmonary Langerhans cell histiocytosis To assess the impact of tobacco discontinuation Study Design Multicentric prospective cohort study Main endpoint: Pulmonary deterioration Sample size : 40 patients
Sponsor: Assistance Publique - Hôpitaux de Paris
Current Primary Outcome: Pulmonary deterioration [ Time Frame: 2 years ]
Original Primary Outcome: Pulmonary deterioration [ Time Frame: 2 years ]
Current Secondary Outcome:
- Evolution of pulmonary volumes (FEV1) [ Time Frame: 6 months ]
- Evolution of pulmonary lesions in High Resolution Computed Tomography (HRCT) [ Time Frame: 6 months ]
Original Secondary Outcome:
Information By: Assistance Publique - Hôpitaux de Paris
Dates:
Date Received: October 12, 2010
Date Started: May 2006
Date Completion:
Last Updated: April 15, 2016
Last Verified: March 2015